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Hospitals run cold. Patient rooms run warm. And nurses? They’re constantly moving. When temperatures fluctuate as often as your tasks, layering isn’t just smart—it's essential.
Enter the scrub vest: a low-bulk layer that keeps your core warm without slowing you down. In this guide, we’ll cover everything you need to know about scrub vests, why nurses love them, how they compare to jackets and what features to look for when finding the right one for your shift.
Why Layering Matters on Shift
Whether you’re walking into a 6 a.m. start or rounding at midnight, staying comfortable through changing temps can make or break your day. That’s where smart layers—like scrub vests—come in.
Comfort that Adapts with You
Hospitals and clinics are full of microclimates. Cold breakrooms, warm patient bays, breezy hallways. Add in the adrenaline rush of your shift, and your body temp is constantly adjusting. That’s why scrub vests make so much sense: they bring warmth that helps you stay comfortable without overheating when things get busy.
Flexibility Without Restriction
Unlike jackets, scrub vests keep your core warm while giving your arms full range of motion. That means less bunching, less bulk and more ease throughout your day. Whether you’re checking vitals, assisting with transfers or hustling between rooms, the sleeveless design lets you move more freely—all while keeping your uniform modern and polished.
Scrub Jackets vs. Vests: Which Layer Works for You?
There’s no one-size-fits-all when it comes to layering over scrubs. What works for night shift in the ICU might feel like overkill during a fast-paced day in the ER. The right choice depends on your unit, your role and how much coverage you need. Let’s break it down.
Jackets: Full Coverage for Cold Conditions
Scrub jackets are made for the coldest conditions—overnight shifts, early starts or units that always feel like the AC is blasting. With long sleeves, zip-fronts and cozy linings, they give you full coverage when you really need to bundle up.
Vests: Core Warmth with Full Mobility
Scrub vests give you the best of both worlds: warmth where it matters and freedom where it counts. By keeping your core insulated and your arms free, they’re perfect for staying comfortable while staying quick on your feet.
Style That Works Across Shifts
Layering is personal. From nurse practitioners to RNs and respiratory therapists, the right choice depends on your unit, your schedule and how much movement your day demands. A scrub vest adds structure to your uniform while keeping things low-bulk and streamlined, while jackets bring that extra warmth when conditions call for it.
Many pros keep both in rotation—jackets for the chill, vests for mobility. Whether you’re loyal to one or building your layering lineup, Cherokee offers flexible options to fit your needs. Check out our men’s and women's scrub jackets and vests to find the layer that works for you.
iflex by Cherokee
$32.80
Price reduced from
$41.00
9 Colors
FORM by Cherokee
$41.97
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to
$56.00
Price reduced from
$70.00
6 Colors
Professionals by Cherokee Workwear
$24.00
Price reduced from
$30.00
13 Colors
Revolution by Cherokee Workwear
$30.40
Price reduced from
$38.00
5 Colors
What to Look for in a Scrub Vest
The right vest should do more than just keep you warm. It should feel like part of your uniform—adding comfort, storage and flexibility without adding bulk. Whether you're shopping for your first layer or replacing an old favorite, here’s what to consider.
1. Fabric & Fit
Your vest should move with you, not against you. Look for performance fabric blends that offer stretch, breathability and long-lasting structure. Cherokee’s scrub vests are made with lightweight knits and durable woven fabrics that feel soft but hold their shape, shift after shift. To dive deeper into fabric types and what they mean for your workday, check out our guide to different scrub materials.
Fit matters too. Whether you like a snug silhouette or something more relaxed, Cherokee offers inclusive sizing options like petite, tall and extended sizes for all body types—so you can find the right fit without compromise.
2. Pockets & Practicality
When it comes to your uniform, storage isn’t optional. From pens and trauma shears to alcohol swabs and tape, you’ve got a lot to carry—and your vest should hold it all. Look for styles with secure zip pockets or deep, top-entry spots to keep gear from falling out. Cherokee designs multi-pocket scrubs with function in mind, so you can keep essentials close and organized without feeling bulky.
3. Easy Care
Scrub vests should work as hard as you do—and that includes laundry day. Look for vests made to withstand frequent washes without losing their shape, stretch or softness. No dry-cleaning labels. No special treatment needed.
4. Size Inclusivity
Everyone deserves a vest that fits and feels good. Cherokee offers sizes from XXS to 5XL in a range of silhouettes and lengths, so every nurse can layer with confidence. Because comfort should never be one-size-fits-all.
Why Nurses Are Choosing to Layer
Staying warm isn’t always easy on shift. From freezing breakrooms to unpredictable unit temps, nurses are constantly adapting to their environment. That’s why scrub layers have become go-to essentials for comfort and focus. Even with thermals, the chill can linger. A lightweight, insulating vest gives you just enough warmth without adding bulk or slowing you down.
How to Style a Scrub Vest
Scrub vests don't just add warmth—they add polish and personal style. Whether you’re elevating your uniform or creating a more intentional look, smart layering helps you feel more confident, comfortable and pulled together all shift long.
Color Coordination
Keep things cohesive by pairing your vest with scrub tops and scrub pants in matching or complementary shades. Classic neutrals like black, navy and charcoal always look polished, while soft tones like teal or pewter add personality without going overboard.
Feeling bold? Try seasonal colors that pop and still feel professional. And if you love a monochrome look, mix shades within the same color family—like navy and ceil—for an outfit that’s both easy and elevated.
Shift-to-Street Style
Scrub vests aren’t just for work. They layer just as easily over a tee and joggers when you’re grabbing coffee or running errands on the way home. It’s comfort that transitions effortlessly, so you stay moving without missing a beat.
Where to Shop the Look
Layering isn’t just about staying warm—it's about feeling prepared, comfortable and confident every step of your shift. Whether you’re new to the floor or have years of experience, the right vest or jacket can make all the difference.
Ready to level up your layers? Explore Cherokee's full range of women's scrubs and men's scrubs to find styles that work as hard as you do. From scrub jackets for full coverage to scrub vests that keep you moving, Cherokee’s got you covered.